β-Arrestin-Mediated Angiotensin II Type 1 Receptor Activation Promotes Pulmonary Vascular Remodeling in Pulmonary Hypertension.
第一作者:
Zhiyuan,Ma
第一单位:
Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.
作者:
关键词
AT1R, Angiotensin II type 1 receptorAngII, Angiotensin-2Beta-arrestinBrdU, bromodeoxyuridineG protein–coupled receptorGPCR, G protein–coupled receptorLV, left ventricularMCT, monocrotalinePAH, pulmonary arterial hypertensionPASMCs, pulmonary artery smooth muscle cellsPBS, phosphate-buffered salinePV, pressure-volumeRV, right ventricularSMC, smooth muscle cellTRV023, TRV120023angiotensinbiased agonismpulmonary arterial hypertensionrRNA, ribosomal RNA
DOI
10.1016/j.jacbts.2021.09.006
PMID
34869949
发布时间
2021-12-07
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JACC. Basic to translational science
2021年6卷11期
854-869页
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