Plasma Lead Concentration and Risk of Late Kidney Allograft Failure: Findings From the TransplantLines Biobank and Cohort Studies.

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作者： Camilo G,Sotomayor ^[1] ; Flavia,Giubergia ^[2] ; Dion,Groothof ^[3] ; Catterina,Ferreccio ^[4] ; Ilja M,Nolte ^[5] ; Gerjan J,Navis ^[3] ; Antonio W,Gomes-Neto ^[3] ; Daan,Kremer ^[3] ; Tim J,Knobbe ^[3] ; Michele F,Eisenga ^[3] ; Ramón,Rodrigo ^[2] ; Daan J,Touw ^[6] ; Stephan J L,Bakker ^[3] ; TransplantLines Investigators

作者单位： Division of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Program of Integrative Biology, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile; Radiology Department, Clinical Hospital University of Chile, University of Chile, Santiago, Chile. Electronic address: c.g.sotomayor.campos@umcg.nl. ^[1] Molecular and Clinical Pharmacology Program, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile. ^[2] Division of Nephrology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. ^[3] Advanced Center for Chronic Diseases, Pontificia Universidad Católica de Chile, Santiago, Chile. ^[4] Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. ^[5] Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. ^[6]

关键词 Lead allograft function end-stage renal disease (ESRD)heavy metal exposure kidney transplant recipient late graft failure modifiable risk factor nephrotoxicity oxidative stress