Long-acting capsid inhibitor protects macaques from repeat SHIV challenges.

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第一作者： Samuel J,Vidal

第一单位： Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.;Division of Infectious Diseases, Brigham and Women's Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

作者： Samuel J,Vidal ^[1] ; Elena,Bekerman ^[2] ; Derek,Hansen ^[2] ; Bing,Lu ^[2] ; Kelly,Wang ^[2] ; Judy,Mwangi ^[2] ; William,Rowe ^[2] ; Federico,Campigotto ^[2] ; Jim,Zheng ^[2] ; Darryl,Kato ^[2] ; Abishek,Chandrashekar ^[3] ; Julia,Barrett ^[3] ; Shivani,Patel ^[3] ; Huahua,Wan ^[3] ; Tochi,Anioke ^[3] ; Noe B,Mercado ^[3] ; Joseph P,Nkolola ^[3] ; Melissa J,Ferguson ^[4] ; William J,Rinaldi ^[4] ; Christian,Callebaut ^[2] ; Wade,Blair ^[2] ; Tomas,Cihlar ^[2] ; Romas,Geleziunas ^[2] ; Stephen R,Yant ^[5] ; Dan H,Barouch ^[6]

作者单位： Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.;Division of Infectious Diseases, Brigham and Women's Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. ^[1] Gilead Sciences, Foster City, CA, USA. ^[2] Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. ^[3] Alpha Genesis, Inc., Yemassee, SC, USA. ^[4] Gilead Sciences, Foster City, CA, USA. stephen.yant@gilead.com. ^[5] Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. dbarouch@bidmc.harvard.edu.;Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. dbarouch@bidmc.harvard.edu. ^[6]

主题词动物(Animals);抗逆转录病毒药(Anti-Retroviral Agents);病毒壳体(Capsid);衣壳蛋白质类(Capsid Proteins);猕猴(Macaca mulatta);猴获得性免疫缺陷综合征(Simian Acquired Immunodeficiency Syndrome)

DOI 10.1038/s41586-021-04279-4

PMID 34875675

发布时间 2024-03-02

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准确一般字义偏差语意偏离译文作用小提交