首页> Brain research> Sodium butyrate attenuates rotenone-induced toxicity by activation of autophagy through epigenetically regulating PGC-1α expression in PC12 cells.

Sodium butyrate attenuates rotenone-induced toxicity by activation of autophagy through epigenetically regulating PGC-1α expression in PC12 cells.

导出 LinkOut

翻译打印收藏纠错

第一作者： Yi,Zhang

第一单位： Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China. Electronic address: zhangyi9102@126.com.

作者： Yi,Zhang ^[1] ; Shaoqing,Xu ^[2] ; Yiwei,Qian ^[3] ; Xiaoqin,He ^[4] ; Chengjun,Mo ^[5] ; Xiaodong,Yang ^[6] ; Qin,Xiao ^[7]

作者单位： Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China. Electronic address: zhangyi9102@126.com. ^[1] Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China. Electronic address: shaoqingfx@163.com. ^[2] Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China. Electronic address: qyw12344@rjh.com.cn. ^[3] Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China. Electronic address: 18176329672@163.com. ^[4] Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China. Electronic address: mochengjun97@163.com. ^[5] Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China. Electronic address: yangxiaodong2011@yeah.net. ^[6] Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197 Ruijin Er Road, Shanghai 200025, China. Electronic address: xq10537@rjh.com.cn. ^[7]

关键词 Autophagy Histone acetylation modification Parkinson’s disease Peroxisome proliferator-activated receptor γ coactivator 1α Short-chain fatty acid