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Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency, CD8<sup>+</sup> TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas.

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作者: Karolin,Heinze [1] ; Tayyebeh M,Nazeran [2] ; Sandra,Lee [2] ; Pauline,Krämer [3] ; Evan S,Cairns [1] ; Derek S,Chiu [4] ; Samuel Cy,Leung [1] ; Eun Young,Kang [2] ; Nicola S,Meagher [2] ; Catherine J,Kennedy [3] ; Jessica,Boros [5] ; Friedrich,Kommoss [6] ; Hans-Walter,Vollert [7] ; Florian,Heitz [8] ; Andreas,du Bois [7] ; Philipp,Harter [8] ; Marcel,Grube [9] ; Bernhard,Kraemer [10] ; Annette,Staebler [11] ; Felix Kf,Kommoss [11] ; Sabine,Heublein [11] ; Hans-Peter,Sinn [1] ; Naveena,Singh [4] ; Angela,Laslavic [4] ; Esther,Elishaev [12] ; Alex,Olawaiye [13] ; Kirsten,Moysich [14] ; Francesmary,Modugno [13] ; Raghwa,Sharma [15] ; Alison H,Brand [16] ; Paul R,Harnett [17] ; Anna,DeFazio [16] ; Renée T,Fortner [18] ; Jan,Lubinski [16] ; Marcin,Lener [19] ; Aleksandra,Tołoczko-Grabarek [20] ; Cezary,Cybulski [21] ; Helena,Gronwald [8] ; Jacek,Gronwald [20] ; Penny,Coulson [8] ; Mona A,El-Bahrawy [22] ; Michael E,Jones [7] ; Minouk J,Schoemaker [8] ; Anthony J,Swerdlow [20] ; Kylie L,Gorringe [23] ; Ian,Campbell [24] ; Linda,Cook [25] ; Simon A,Gayther [25] ; Michael E,Carney [25] ; Yurii B,Shvetsov [25] ; Brenda Y,Hernandez [26] ; Lynne R,Wilkens [25] ; Marc T,Goodman [27] ; Constantina,Mateoiu [28] ; Anna,Linder [27] ; Karin,Sundfeldt [27] ; Linda E,Kelemen [27] ; Aleksandra,Gentry-Maharaj [29] ; Martin,Widschwendter [30] ; Usha,Menon [31] ; Kelly L,Bolton [30] ; Jennifer,Alsop [32] ; Mitul,Shah [33] ; Mercedes,Jimenez-Linan [34] ; Paul Dp,Pharoah [35] ; James D,Brenton [36] ; Kara L,Cushing-Haugen [36] ; Holly R,Harris [36] ; Jennifer A,Doherty [37] ; Blake,Gilks [38] ; Prafull,Ghatage [38] ; David G,Huntsman [38] ; Gregg S,Nelson [39] ; Anna V,Tinker [40] ; Cheng-Han,Lee [41] ; Ellen L,Goode [42] ; Brad H,Nelson [40] ; Susan J,Ramus [43] ; Stefan,Kommoss [44] ; Aline,Talhouk [45] ; Martin,Köbel [45] ; Michael S,Anglesio [44]
作者单位: Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, Canada. [1] University of British Columbia, Vancouver General Hospital, and BC Cancer. British Columbia's Gynecological Cancer Research Team (OVCARE), Vancouver, Canada. [2] Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Canada. [3] Department of Women's Health, University Hospital Tübingen, Tübingen, Germany. [4] University of New South Wales, Adult Cancer Program, Lowy Cancer Research Centre, Sydney, Australia. [5] University of New South Wales, School of Women's and Children's Health, Sydney, Australia. [6] The University of Sydney, Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, Australia. [7] Department of Gynaecological Oncology, Westmead Hospital, Sydney, Australia. [8] Medizin Campus Bodensee, Institute of Pathology, Friedrichshafen, Germany. [9] Department of Gynecology and Obstetrics, Medizin Campus Bodensee, Friedrichshafen, Germany. [10] Department of Gynecology and Gynecologic Oncology, Kliniken Essen Mitte, Essen, Germany. [11] University Hospital Tübingen, Institute of Pathology and Neuropathology, Tübingen, Germany. [12] University Hospital Heidelberg, Institute of Pathology, Heidelberg, Germany. [13] Department of Obstetrics and Gynecology, University Hospital Heidelberg and National Center for Tumor Diseases, Heidelberg, Germany. [14] Department of Pathology, Barts Health National Health Service Trust, London, UK. [15] Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. [16] Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. [17] Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA. [18] Westmead Hospital, Tissue Pathology and Diagnostic Oncology, Sydney, Australia. [19] University of Sydney, Sydney, Australia. [20] Western Sydney University, Sydney, Australia. [21] Westmead Hospital, Crown Princess Mary Cancer Centre, Sydney, Australia. [22] The Daffodil Centre, The University of Sydney, A Joint Venture with Cancer Council NSW, Sydney, Australia. [23] Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. [24] Department of Genetics and Pathology, International Hereditary Cancer Centre, Pomeranian Medical University, Szczecin, Poland. [25] Department of Propaedeutics, Physical Diagnostics and Dental Physiotherapy, Pomeranian Medical University, Szczecin, Poland. [26] Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. [27] Department of Metabolism, Digestion and Reproduction, Hammersmith Hospital, Imperial College London, London, UK. [28] Division of Breast Cancer Research, The Institute of Cancer Research, London, UK. [29] Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Australia. [30] Peter MacCallum Cancer Centre, Women's Cancer Program, Melbourne, Australia. [31] Peter MacCallum Cancer Centre, Cancer Genetics Laboratory, Research Division, Melbourne, Australia. [32] Division of Epidemiology and Biostatistics, The University of New Mexico, Albuquerque, NM, USA. [33] Cedars-Sinai Medical Center, Center for Bioinformatics and Functional Genomics and the Cedars Sinai Genomics Core, Los Angeles, CA, USA. [34] Department of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA. [35] University of Hawaii Cancer Center, Epidemiology Program, Honolulu, HI, USA. [36] Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Cancer Prevention and Genetics Program, Los Angeles, CA, USA. [37] Department of Obstetrics and Gynecology, Sahlgrenska Academy at Gothenburg University, Sahlgrenska Center for Cancer Research, Gothenburg, Sweden. [38] Hollings Cancer Center and Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA. [39] University College London, MRC Clinical Trials Unit at UCL, Institute of Clinical Trials &amp; Methodology, London, UK. [40] University College London, Department of Women's Cancer, Institute for Women's Health, London, UK. [41] University of Innsbruck, EUTOPS Institute, Innsbruck, Austria. [42] Department of Hematology and Oncology, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA. [43] Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. [44] Department of Histopathology, Addenbrookes Hospital, Cambridge, UK. [45] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [46] University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK. [47] Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. [48] Huntsman Cancer Institute, Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA. [49] Department of Oncology, Division of Gynecologic Oncology, University of Calgary, Calgary, Canada. [50] Department of Medicine, University of British Columbia, Vancouver, Canada. [51] University of Alberta, Department of Laboratory Medicine and Pathology, Edmonton, Canada. [52] Division of Epidemiology, Department of Health Science Research, Mayo Clinic, Rochester, MN, USA. [53] Trev &amp; Joyce Deeley Research Centre, British Columbia Cancer Agency, Victoria, Canada. [54]
DOI 10.1002/path.5849
PMID 34897700
发布时间 2024-06-15
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