Subunit-Specific Reactivity of Autoantibodies Against Laminin-332 Reveals Direct Inflammatory Mechanisms on Keratinocytes.

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作者： Lei,Bao ^[1] ; Jing,Li ^[2] ; Farzan,Solimani ^[3] ; Dario,Didona ^[4] ; Payal M,Patel ^[3] ; Xiaoguang,Li ^[2] ; Hua,Qian ^[5] ; Norito,Ishii ^[5] ; Takashi,Hashimoto ^[6] ; Michael,Hertl ^[6] ; Kyle T,Amber ^[7]

作者单位： Department of Dermatology, University of Illinois at Chicago, Chicago, IL, United States. ^[1] Division of Dermatology, Rush University Medical Center, Chicago, IL, United States. ^[2] Department of Dermatology and Allergology, Philipps University, Marburg, Germany. ^[3] Department of Dermatology, Venereology and Allergology, Charitè-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. ^[4] Central Laboratory, Dermatology Hospital of Jiangxi Province, Dermatology Institute of Jiangxi Province, and the Affiliated Dermatology Hospital of Nanchang University, Nanchang, China. ^[5] Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, Kurume, Japan. ^[6] Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan. ^[7] Department of Internal Medicine, Rush University Medical Center, Chicago, IL, United States. ^[8]

关键词 RNA-seq autoimmune blistering diseases immunobullous disease keratinocyte laminin-332 pemphigoid