Effect of Amino Acid Substitutions on 70S Ribosomal Binding, Cellular Uptake, and Antimicrobial Activity of Oncocin Onc112.

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作者： Lisa,Kolano ^[1] ; Daniel,Knappe ^[2] ; Angela,Berg ^[1] ; Thorsten,Berg ^[3] ; Ralf,Hoffmann ^[4]

作者单位： Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, 04103, Leipzig, Germany. ^[1] Center for Biotechnology and Biomedicine, Universität Leipzig, 04103, Leipzig, Germany. ^[2] Enbiotix GmbH, 04103, Leipzig, Germany. ^[3] Institute of Organic Chemistry, Universität Leipzig, 04103, Leipzig, Germany. ^[4]

关键词 Onc112 fluorescence polarization (FP)label-free quantitation oncocin proline-rich antimicrobial peptide (PrAMP)

主题词氨基酸取代(Amino Acid Substitution);抗菌药(Anti-Bacterial Agents);抗微生物阳离子肽类(Antimicrobial Cationic Peptides);微生物敏感性试验(Microbial Sensitivity Tests);核糖体(Ribosomes)

DOI 10.1002/cbic.202100609

PMID 34902208

发布时间 2022-07-29

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