Discovery of an ancient MHC category with both class I and class II features.

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作者： Kazuhiko,Okamura ^[1] ; Johannes M,Dijkstra ^[2] ; Kentaro,Tsukamoto ^[3] ; Unni,Grimholt ^[4] ; Geert F,Wiegertjes ^[5] ; Akiko,Kondow ^[6] ; Hisateru,Yamaguchi ^[7] ; Keiichiro,Hashimoto ^[8]

作者单位： Faculty of Clinical Engineering, School of Health Sciences, Fujita Health University, Toyoake 470-1192, Japan. ^[1] Institute for Comprehensive Medical Science, Fujita Health University, Toyoake 470-1192, Japan. ^[2] Laboratory for Proteins and Genes, Center for Joint Research Facilities Support, Fujita Health University, Toyoake 470-1192, Japan. ^[3] Fish Health Research Group, Norwegian Veterinary Institute 1433 Aas, Norway. ^[4] Aquaculture and Fisheries Group, Department of Animal Sciences, Wageningen University and Research, 6700 AH Wageningen, The Netherlands. ^[5] Advanced Comprehensive Research Organization, Teikyo University, Tokyo 173-0003, Japan. ^[6] Department of Medical Technology, School of Nursing and Medical Care, Yokkaichi Nursing and Medical Care University, Yokkaichi 512-8045, Japan. ^[7] Emeritus Professor of Department of Biomedical Polymer Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake 470-1192, Japan keihashi@fujita-hu.ac.jp. ^[8]

关键词 MHC class I MHC class II MHC class divergence major histocompatibility complex molecular evolution