The safety and efficacy of gene therapy treatment for monogenic retinal and optic nerve diseases: A systematic review.

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第一作者： Alexis Ceecee,Britten-Jones

第一单位： Department of Optometry and Vision Sciences, Melbourne School of Health Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia; Department of Surgery (Ophthalmology), Melbourne Medical School, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia. Electronic address: ac.brittenjones@unimelb.edu.au.

作者： Alexis Ceecee,Britten-Jones ^[1] ; Rui,Jin ^[2] ; Sena A,Gocuk ^[3] ; Elise,Cichello ^[4] ; Fleur,O'Hare ^[3] ; Doron G,Hickey ^[4] ; Thomas L,Edwards ^[5] ; Lauren N,Ayton ^[3]

作者单位： Department of Optometry and Vision Sciences, Melbourne School of Health Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia; Department of Surgery (Ophthalmology), Melbourne Medical School, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia. Electronic address: ac.brittenjones@unimelb.edu.au. ^[1] Department of Optometry and Vision Sciences, Melbourne School of Health Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia. ^[2] Department of Optometry and Vision Sciences, Melbourne School of Health Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia; Department of Surgery (Ophthalmology), Melbourne Medical School, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia. ^[3] Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia. ^[4] Department of Surgery (Ophthalmology), Melbourne Medical School, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, Victoria, Australia; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia. ^[5]

关键词 Gene therapy Inherited retinal disease Luxturna Retinal dystrophy Systematic review

主题词色觉缺陷(Color Vision Defects);人类(Humans);视神经疾病(Optic Nerve Diseases);视网膜(Retina);视网膜营养不良(Retinal Dystrophies)

DOI 10.1016/j.gim.2021.10.013

PMID 34906485

发布时间 2022-03-23

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