Data Centric Molecular Analysis and Evaluation of Hepatocellular Carcinoma Therapeutics Using Machine Intelligence-Based Tools.

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第一作者： Rengul,Cetin-Atalay

第一单位： Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL, 60637, USA. rengul@uchicago.edu.

作者： Rengul,Cetin-Atalay ^[1] ; Deniz Cansen,Kahraman ^[2] ; Esra,Nalbat ^[3] ; Ahmet Sureyya,Rifaioglu ^[4] ; Ahmet,Atakan ^[5] ; Ataberk,Donmez ^[5] ; Heval,Atas ^[6] ; M Volkan,Atalay ^[5] ; Aybar C,Acar ^[7] ; Tunca,Doğan ^[3]

作者单位： Section of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, IL, 60637, USA. rengul@uchicago.edu. ^[1] Cancer Systems Biology Laboratory, Graduate School of Informatics, METU, Ankara, 06800, Turkey. cansen@metu.edu.tr. ^[2] Cancer Systems Biology Laboratory, Graduate School of Informatics, METU, Ankara, 06800, Turkey. ^[3] Department of Computer Engineering, Iskenderun Technical University, Iskenderun, Hatay, 31200, Turkey. ^[4] Department of Computer Engineering, METU, Ankara, 06800, Turkey. ^[5] Department of Computer Engineering, EBYU, Ankara, 24002, Turkey. ^[6] Department of Computer Science, University of Maryland, College Park, MD, 20742, USA. ^[7] Cancer Systems Biology Laboratory, Graduate School of Informatics, METU, Ankara, 06800, Turkey. tuncadogan@hacettepe.edu.tr. ^[8] Department of Computer Engineering, Hacettepe University, Ankara, 06800, Turkey. tuncadogan@hacettepe.edu.tr. ^[9]

关键词 Artificial intelligence Drug discovery and repurposing Hepatocellular carcinoma Knowledge graphs Machine learning

主题词抗肿瘤药(Antineoplastic Agents);人工智能(Artificial Intelligence);癌, 肝细胞(Carcinoma, Hepatocellular);计算生物学(Computational Biology);人类(Humans);肝肿瘤(Liver Neoplasms);分子靶向治疗(Molecular Targeted Therapy)

DOI 10.1007/s12029-021-00768-x

PMID 34910274

发布时间 2022-02-16

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