Single ascending dose safety, tolerability, and pharmacokinetic study of econazole in healthy volunteers.

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作者： Himanshi,Khera ^[1] ; Avaneesh Kumar,Pandey ^[1] ; Nusrat,Shafiq ^[1] ; G K,Khuller ^[2] ; Ritika,Kondel Bhandari ^[1] ; Aditi,Panditrao ^[1] ; Nanda,Gamad ^[1] ; Rachna,Rohilla ^[1] ; Samiksha,Bhattacharjee ^[1] ; Naveen,Murali ^[1] ; Harish,Cvn ^[1] ; Devraj,Belavagi ^[1] ; Chakrant,Mothsara ^[1] ; Manjula,Singh ^[3] ; Navneet,Sharma ^[4] ; Digamber,Behera ^[5] ; Samir,Malhotra ^[1]

作者单位： Department of Pharmacology, Pgimer, Chandigarh, India. ^[1] Department of Biochemistry, PGIMER, Chandigarh, India. ^[2] Division of ECD, Indian Council of Medical Research, New Delhi, India. ^[3] Department of Internal Medicine, Pgimer, Chandigarh, India. ^[4] Department of Pulmonary Medicine, PGIMER, Chandigarh, India. ^[5]

关键词 Econazole Phase 1 study healthy volunteers multi drug resistant tuberculosis pharmacokinetic evaluation

主题词曲线下面积(Area Under Curve);剂量效应关系, 药物(Dose-Response Relationship, Drug);双盲法(Double-Blind Method);益康唑(Econazole);人类(Humans)

DOI 10.1080/14787210.2022.2016392

PMID 34913825

发布时间 2022-06-01

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