Response to Pembrolizumab After Dose-Reduced Cisplatin Plus Gemcitabine Chemotherapy Is Inferior to That After Carboplatin Plus Gemcitabine Chemotherapy in Cisplatin-Unfit Patients With Advanced Urothelial Carcinoma.

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作者： Makito,Miyake ^[1] ; Takuto,Shimizu ^[2] ; Nobutaka,Nishimura ^[2] ; Keisuke,Kiba ^[3] ; Fumisato,Maesaka ^[4] ; Yuki,Oda ^[5] ; Akira,Tachibana ^[6] ; Mitsuru,Tomizawa ^[7] ; Chihiro,Ohmori ^[8] ; Yoshiaki,Matsumura ^[8] ; Kazuki,Ichikawa ^[9] ; Shinichiro,Mizobuchi ^[10] ; Takanosuke,Yoshikawa ^[11] ; Shunta,Hori ^[2] ; Yosuke,Morizawa ^[2] ; Daisuke,Gotoh ^[2] ; Yasushi,Nakai ^[2] ; Satoshi,Anai ^[2] ; Kazumasa,Torimoto ^[2] ; Katsuya,Aoki ^[2] ; Nobumichi,Tanaka ^[12] ; Kiyohide,Fujimoto ^[2] ; Nara Urological Research and Treatment Group

作者单位： Department of Urology, Nara Medical University, Kashihara, Nara, Japan. Electronic address: makitomiyake@yahoo.co.jp. ^[1] Department of Urology, Nara Medical University, Kashihara, Nara, Japan. ^[2] Department of Urology, Kindai University Nara Hospital, Ikoma, Nara, Japan. ^[3] Department of Urology, Nara City Hospital, Nara, Japan. ^[4] Department of Urology, Nara Prefecture Seiwa Medical Center, Nara, Japan. ^[5] Department of Urology, Osaka Kaisei Hospital, Yodogawa, Osaka, Japan. ^[6] Department of Urology, Yamatotakada Municipal Hospital, Yamatotakada, Nara, Japan. ^[7] Department of Urology, Nara Prefecture General Medical Center, Nara, Japan. ^[8] Department of Urology, Koseikai Takai Hospital, Tenri, Japan. ^[9] Department of Urology, Tane General Hospital, Osaka, Japan. ^[10] Department of Urology, Matsusaka Chuo General Hospital, Matsusaka, Mie, Japan. ^[11] Department of Urology, Nara Medical University, Kashihara, Nara, Japan; Department of Prostate Brachytherapy, Nara Medical University, Kashihara, Nara, Japan. ^[12]

关键词 First-line Immune checkpoint inhibitor Platinum Survival Urinary bladder neoplasms

主题词抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);卡铂(Carboplatin);癌, 移行细胞(Carcinoma, Transitional Cell);顺铂(Cisplatin);脱氧胞苷(Deoxycytidine);人类(Humans);膀胱肿瘤(Urinary Bladder Neoplasms)

DOI 10.1016/j.clgc.2021.11.006

PMID 34916166

发布时间 2022-12-07

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