TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.

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作者： Manling,Xie ^[1] ; Yong U,Liu ^[2] ; Shunyi,Zhao ^[3] ; Lingxin,Zhang ^[4] ; Dale B,Bosco ^[1] ; Yuan-Ping,Pang ^[5] ; Jun,Zhong ^[1] ; Udit,Sheth ^[6] ; Yuka A,Martens ^[7] ; Na,Zhao ^[2] ; Chia-Chen,Liu ^[8] ; Yongxian,Zhuang ^[8] ; Liewei,Wang ^[8] ; Dennis W,Dickson ^[8] ; Mark P,Mattson ^[5] ; Guojun,Bu ^[5] ; Long-Jun,Wu ^[8]

作者单位： Department of Neurology, Mayo Clinic, Rochester, MN, USA. ^[1] Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA. ^[2] Department of Neurology, Mayo Clinic, Rochester, MN, USA. liuy6@foxmail.com. ^[3] Laboratory for Neuroscience in Health and Disease, Guangzhou First People's Hospital School of Medicine, South China University of Technology, Guangzhou, China. liuy6@foxmail.com. ^[4] Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, USA. ^[5] Computer-Aided Molecular Design Laboratory, Mayo Clinic, Rochester, MN, USA. ^[6] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. ^[7] Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. ^[8] Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA. ^[9] Department of Neurology, Mayo Clinic, Rochester, MN, USA. wu.longjun@mayo.edu. ^[10] Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. wu.longjun@mayo.edu. ^[11] Department of Immunology, Mayo Clinic, Rochester, MN, USA. wu.longjun@mayo.edu. ^[12]