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Particles in Biopharmaceutical Formulations, Part 2: An Update on Analytical Techniques and Applications for Therapeutic Proteins, Viruses, Vaccines and Cells.

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第一作者： Alexandra,Roesch

第一单位： Coriolis Pharma, Fraunhoferstr. 18 b, 82152 Martinsried, Germany; Leiden Academic Centre for Drug Research (LACDR), Leiden University, PO Box 9502, 2300, RA, Leiden, the Netherlands.

作者： Alexandra,Roesch ^[1] ; Sarah,Zölls ^[2] ; Daniela,Stadler ^[2] ; Constanze,Helbig ^[2] ; Klaus,Wuchner ^[3] ; Gideon,Kersten ^[1] ; Andrea,Hawe ^[2] ; Wim,Jiskoot ^[1] ; Tim,Menzen ^[4]

作者单位： Coriolis Pharma, Fraunhoferstr. 18 b, 82152 Martinsried, Germany; Leiden Academic Centre for Drug Research (LACDR), Leiden University, PO Box 9502, 2300, RA, Leiden, the Netherlands. ^[1] Coriolis Pharma, Fraunhoferstr. 18 b, 82152 Martinsried, Germany. ^[2] Janssen Research and Development, DPD&S Biotherapeutics Development, Hochstr. 201, 8200 Schaffhausen, Switzerland. ^[3] Coriolis Pharma, Fraunhoferstr. 18 b, 82152 Martinsried, Germany. Electronic address: Tim.Menzen@coriolis-pharma.com. ^[4]

关键词 Biopharmaceutical characterization Lipid Nanoparticle(s) (LNP)Microparticle(s)Nanoparticle(s)Particle size Protein aggregation Protein formulation(s)Protein(s)Vaccine(s)Viral vector(s)

医学主题词生物制品(Biological Products);药物调剂(Drug Compounding);脂质体(Liposomes);纳米粒子(Nanoparticles);粒子大小(Particle Size);疫苗(Vaccines);病毒(Viruses)

DOI 10.1016/j.xphs.2021.12.011

PMID 34919969

发布时间 2022-04-25

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准确一般字义偏差语意偏离译文作用小提交