SARS-CoV-2 spike engagement of ACE2 primes S2' site cleavage and fusion initiation.

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作者： Shi,Yu ^[1] ; Xu,Zheng ^[2] ; Bingjie,Zhou ^[1] ; Juan,Li ^[2] ; Mengdan,Chen ^[2] ; Rong,Deng ^[1] ; Gary,Wong ^[2] ; Dimitri,Lavillette ^[1] ; Guangxun,Meng ^[2]

作者单位： The Center for Microbes, Development and Health, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China. ^[1] CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China. ^[2] CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China; dlaville@ips.ac.cn gxmeng@ips.ac.cn. ^[3] Pasteurien College, Soochow University, Suzhou, Jiangsu 215006, China. ^[4] Nanjing Unicorn Academy of Innovation, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Nanjing, Jiangsu 211135, China. ^[5] The Center for Microbes, Development and Health, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China; dlaville@ips.ac.cn gxmeng@ips.ac.cn. ^[6]

关键词 ACE2 S2′SARS-CoV-2 spike membrane fusion spike protein