Small-molecule degraders of cyclin-dependent kinase protein: a review.

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第一作者： Bin,Yu

第一单位： Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China.

作者： Bin,Yu ^[1] ; Zekun,Du ^[1] ; Yuming,Zhang ^[1] ; Zhiyu,Li ^[1] ; Jinlei,Bian ^[1]

作者单位： Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, PR China. ^[1]

关键词 PROTAC degraders cyclin-dependent kinase inhibitors glue degraders protein degradation ubiquitin-proteasome system

主题词细胞周期蛋白质依赖激酶类(Cyclin-Dependent Kinases);人类(Humans);分子结构(Molecular Structure);蛋白激酶抑制剂(Protein Kinase Inhibitors);小分子化合物库(Small Molecule Libraries)

DOI 10.4155/fmc-2021-0154

PMID 34939427

发布时间 2022-02-21

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