Blood Immunoproteasome Activity Is Regulated by Sex, Age and in Chronic Inflammatory Diseases: A First Population-Based Study.

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第一作者： Ilona Elisabeth,Kammerl

第一单位： Comprehensive Pneumology Center (CPC), University Hospital, Helmholtz Center Munich, Ludwig-Maximilians-University, 81377 Munich, Germany.;Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), 81377 Munich, Germany.

作者： Ilona Elisabeth,Kammerl ^[1] ; Claudia,Flexeder ^[2] ; Stefan,Karrasch ^[2] ; Barbara,Thorand ^[3] ; Margit,Heier ^[4] ; Annette,Peters ^[5] ; Holger,Schulz ^[6] ; Silke,Meiners ^[7]

作者单位： Comprehensive Pneumology Center (CPC), University Hospital, Helmholtz Center Munich, Ludwig-Maximilians-University, 81377 Munich, Germany.;Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), 81377 Munich, Germany. ^[1] Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), 81377 Munich, Germany.;Institute of Epidemiology, Helmholtz Center Munich, 85764 Neuherberg, Germany.;Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig-Maximilians-University, 80539 Munich, Germany. ^[2] Institute of Epidemiology, Helmholtz Center Munich, 85764 Neuherberg, Germany.;German Center for Diabetes Research (DZD), 85764 Munich, Germany. ^[3] Institute of Epidemiology, Helmholtz Center Munich, 85764 Neuherberg, Germany.;KORA-Study Center, University Hospital Augsburg, 86156 Augsburg, Germany. ^[4] Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), 81377 Munich, Germany.;Institute of Epidemiology, Helmholtz Center Munich, 85764 Neuherberg, Germany.;German Center for Diabetes Research (DZD), 85764 Munich, Germany.;Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-University, 81377 Munich, Germany. ^[5] Comprehensive Pneumology Center (CPC), University Hospital, Helmholtz Center Munich, Ludwig-Maximilians-University, 81377 Munich, Germany.;Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), 81377 Munich, Germany.;Institute of Epidemiology, Helmholtz Center Munich, 85764 Neuherberg, Germany. ^[6] Comprehensive Pneumology Center (CPC), University Hospital, Helmholtz Center Munich, Ludwig-Maximilians-University, 81377 Munich, Germany.;Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), 81377 Munich, Germany.;Research Center Borstel, Leibniz Lung Center, 23845 Sülfeld, Germany.;Airway Research Center North (ARCN), German Center for Lung Research (DZL), 23845 Sülfeld, Germany.;Institute of Experimental Medicine, Christian-Albrechts University Kiel, 24118 Kiel, Germany. ^[7]

关键词 age asthma cardiovascular disease chronic obstructive pulmonary disease (COPD)diabetes immunoproteasome peripheral blood mononuclear cells population-based study sex

主题词年龄因素(Age Factors);血细胞(Blood Cells);慢性病(Chronic Disease);女(雌)性(Female);人类(Humans);炎症(Inflammation);白细胞计数(Leukocyte Count);男(雄)性(Male);中年人(Middle Aged);分子探针(Molecular Probes);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);性别因素(Sex Factors)

DOI 10.3390/cells10123336

PMID 34943847

发布时间 2022-01-04

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Blood Immunoproteasome Activity Is Regulated by Sex, Age and in Chronic Inflammatory Diseases: A First Population-Based Study.

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