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Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1.

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第一作者： Clelia,Mathieu

第一单位： Université Paris-Saclay, CNRS, Institut Galien-Paris Saclay, 92296, Châtenay-Malabry, France.

作者： Clelia,Mathieu ^[1] ; Quentin,Chamayou ^[2] ; Thi Thanh,Hyen Luong ^[2] ; Delphine,Naud ^[3] ; Florence,Mahuteau-Betzer ^[3] ; Mouad,Alami ^[2] ; Elias,Fattal ^[1] ; Samir,Messaoudi ^[2] ; Juliette,Vergnaud-Gauduchon ^[4]

作者单位： Université Paris-Saclay, CNRS, Institut Galien-Paris Saclay, 92296, Châtenay-Malabry, France. ^[1] Université Paris-Saclay, CNRS, BioCIS, 92290, Châtenay, Malabry, France. ^[2] Institut Curie, Université PSL, CNRS UMR9187, Inserm U1196, Chemistry and Modeling for the Biology of Cancer, 91400, Orsay, France; Université Paris-Saclay, CNRS UMR9187, Inserm U1196, Chemistry and Modeling for the Biology of Cancer, 91400, Orsay, France. ^[3] Université Paris-Saclay, CNRS, Institut Galien-Paris Saclay, 92296, Châtenay-Malabry, France. Electronic address: Samir.messaoudi@u-psud.fr. ^[4]

关键词 6BrCaQ Anti-Proliferative activity HSP90 Mitochondrial targeting TRAP1 Triphenylphosphonium TPP