A β-Catenin-TCF-Sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer.

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第一作者： Jeffrey A,Rappaport

第一单位： Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania.

作者： Jeffrey A,Rappaport ^[1] ; Ariana A,Entezari ^[1] ; Adi,Caspi ^[1] ; Signe,Caksa ^[2] ; Aakash V,Jhaveri ^[1] ; Timothy J,Stanek ^[3] ; Adam,Ertel ^[2] ; Joan,Kupper ^[2] ; Paolo M,Fortina ^[2] ; Steven B,McMahon ^[3] ; James B,Jaynes ^[3] ; Adam E,Snook ^[1] ; Scott A,Waldman ^[4]

作者单位： Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania. ^[1] Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania. ^[2] Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania. ^[3] Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, Pennsylvania. Electronic address: scott.waldman@jefferson.edu. ^[4]

关键词 Guanylin Wnt signaling super-enhancer uroguanylin

主题词连环素类(Catenins);结直肠肿瘤(Colorectal Neoplasms);人类(Humans);配体(Ligands);基因座调控区(Locus Control Region);TCF转录因子类(TCF Transcription Factors);β连环素(beta Catenin)

DOI 10.1016/j.jcmgh.2021.12.014

PMID 34954189

发布时间 2022-07-26

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Cellular and molecular gastroenterology and hepatology

2022年13卷4期

1276-1296页

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A β-Catenin-TCF-Sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer.

Cellular and molecular gastroenterology and hepatology

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Cellular and molecular gastroenterology and hepatology

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A β-Catenin-TCF-Sensitive Locus Control Region Mediates GUCY2C Ligand Loss in Colorectal Cancer.

Cellular and molecular gastroenterology and hepatology

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Cellular and molecular gastroenterology and hepatology

相关期刊

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