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首页> European journal of pharmacology> Hepatocyte nuclear factor 4 gamma (HNF4G) is correlated with poor prognosis and promotes tumor cell growth by inhibiting caspase-dependent intrinsic apoptosis in colorectal cancer.

Hepatocyte nuclear factor 4 gamma (HNF4G) is correlated with poor prognosis and promotes tumor cell growth by inhibiting caspase-dependent intrinsic apoptosis in colorectal cancer.

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第一作者： Lu,Chen

第一单位： Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, 200040, China.

作者： Lu,Chen ^[1] ; Huanying,Shi ^[1] ; Xinhai,Wang ^[2] ; Tianxiao,Wang ^[1] ; Yingjie,Wang ^[1] ; Zimei,Wu ^[1] ; Wenxin,Zhang ^[1] ; Haifei,Chen ^[1] ; Mingkang,Zhong ^[1] ; Xiang,Mao ^[3] ; Xiaojin,Shi ^[4] ; Qunyi,Li ^[5]

作者单位： Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, 200040, China. ^[1] Department of Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China. ^[2] Department of Surgery, Huashan Hospital, Fudan University, Shanghai, 200040, China. Electronic address: maoxiang@aliyun.com. ^[3] Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, 200040, China. Electronic address: xiaojin_shi@hotmail.com. ^[4] Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, 200040, China. Electronic address: qyli1234@163.com. ^[5]

关键词 Colorectal cancer (CRC)Hepatocyte nuclear factor 4 gamma (HNF4G)Intrinsic apoptosis Proliferation

主题词动物(Animals);细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶(Caspases);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);结直肠肿瘤(Colorectal Neoplasms);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HCT116细胞(HCT116 Cells);肝细胞核因子4(Hepatocyte Nuclear Factor 4);人类(Humans);小鼠(Mice);小鼠, 裸(Mice, Nude);预后(Prognosis)

DOI 10.1016/j.ejphar.2021.174727

PMID 34965388

发布时间 2022-05-31

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European journal of pharmacology

174727页

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