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Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1.

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第一作者： Agustin,Casimiro-Garcia

第一单位： Medicine Design, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts 02139, United States.

作者： Agustin,Casimiro-Garcia ^[1] ; Christophe,Allais ^[2] ; Agnes,Brennan ^[3] ; Chulho,Choi ^[2] ; Gabriela,Dower ^[3] ; Kathleen A,Farley ^[2] ; Margaret,Fleming ^[3] ; Andrew,Flick ^[2] ; Richard K,Frisbie ^[2] ; Justin,Hall ^[2] ; David,Hepworth ^[1] ; Hannah,Jones ^[1] ; John D,Knafels ^[2] ; Steve,Kortum ^[2] ; Frank E,Lovering ^[1] ; John P,Mathias ^[1] ; Sashi,Mohan ^[3] ; Paul M,Morgan ^[3] ; Chuenlei,Parng ^[1] ; Kevin,Parris ^[2] ; Nick,Pullen ^[3] ; Franklin,Schlerman ^[3] ; John,Stansfield ^[4] ; Joseph W,Strohbach ^[1] ; Felix F,Vajdos ^[2] ; Fabien,Vincent ^[2] ; Hong,Wang ^[2] ; Xiaolun,Wang ^[1] ; Robert,Webster ^[1] ; Stephen W,Wright ^[2]

作者单位： Medicine Design, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts 02139, United States. ^[1] Medicine Design, Pfizer Inc., 445 Eastern Point Rd, Groton, Connecticut 06340, United States. ^[2] Inflammation and Immunology Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts 02139, United States. ^[3] Early Clinical Development Non-Clinical Statistics, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts 02139, United States. ^[4]