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Clinical development of IDH1 inhibitors for cancer therapy.

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第一作者： Mehrdad,Zarei

第一单位： Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, United States; Department of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States.

作者： Mehrdad,Zarei ^[1] ; Jonathan J,Hue ^[2] ; Omid,Hajihassani ^[3] ; Hallie J,Graor ^[3] ; Erryk S,Katayama ^[4] ; Alexander W,Loftus ^[2] ; David,Bajor ^[5] ; Luke D,Rothermel ^[1] ; Ali,Vaziri-Gohar ^[3] ; Jordan M,Winter ^[6]

作者单位： Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, United States; Department of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States. ^[1] Department of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States. ^[2] Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, United States. ^[3] Case Western Reserve University, Cleveland, OH, United States. ^[4] Department of Medicine, Division of Oncology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States. ^[5] Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, United States; Department of Surgery, Division of Surgical Oncology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States. Electronic address: Jordan.Winter@UHHospitals.org. ^[6]

关键词 Cancer Clinical trials Isocitrate dehydrogenase 1 Ivosidenib Review