Immunosuppressive mesenchymal stem cells aggregates incorporating hydrogel microspheres promote an in vitro invasion of cancer cells.
第一作者:
Teruki,Nii
第一单位:
Laboratory of Biomaterials, Institute for Frontier Life and Medical Sciences, Kyoto University, 53 Kawara-cho Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
作者:
关键词
(CCL)5, chemokine (C–C motif) ligand2D, two-dimensional3D, three-dimensionalAnti-cancer drug screeningCAF, cancer-associated fibroblastsCancer invasion modelDDW, double-distilled waterDMEM, Dulbecco's modified Eagle's mediumELISA, enzyme-linked immunosolvent assayFCS, fetal calf serumGM, gelatin hydrogel microspheresGelatin hydrogel microspheresMEM, minimum essential mediumMMP, matrix metalloproteinaseMSC, mesenchymal stem cellsMSC2, MSC of an immunosuppressive phenotypeMesenchymal stem cellsPBS, phosphate buffered-salinePVA, poly (vinyl alcohol)TAM, tumor-associated macrophagesThree-dimensional cell culture
DOI
10.1016/j.reth.2021.11.006
PMID
34977285
发布时间
2022-04-29
- 浏览2
Regenerative therapy
2021年18卷
516-522页
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