Glycolysis/gluconeogenesis specialization in microbes is driven by biochemical constraints of flux sensing.

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第一作者： Severin Josef,Schink

第一单位： Systems Biology Department, Harvard Medical School, Boston, MA, USA.

作者： Severin Josef,Schink ^[1] ; Dimitris,Christodoulou ^[1] ; Avik,Mukherjee ^[2] ; Edward,Athaide ^[1] ; Viktoria,Brunner ^[3] ; Tobias,Fuhrer ^[3] ; Gary Andrew,Bradshaw ^[2] ; Uwe,Sauer ^[2] ; Markus,Basan ^[4]

作者单位： Systems Biology Department, Harvard Medical School, Boston, MA, USA. ^[1] Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland. ^[2] Applied Mathematics Department, Harvard College, Cambridge, MA, USA. ^[3] Laboratory of Systems Pharmacology, Harvard Program in Therapeutic Science, Harvard Medical School, Boston, MA, USA. ^[4]

关键词 flux sensing lag time metabolism specialization trade-off

主题词碳(Carbon);糖原异生(Gluconeogenesis);葡萄糖(Glucose);糖酵解(Glycolysis);恶臭假单胞菌(Pseudomonas putida)

DOI 10.15252/msb.202110704

PMID 34994048

发布时间 2024-04-05

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