Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis.

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第一作者： Shangping,Xing

第一单位： Research Center of Chinese Herbal Resources Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan, Ministry of Education, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.

作者： Shangping,Xing ^[1] ; Feifei,Nong ^[2] ; Yaqin,Wang ^[1] ; Da,Huang ^[1] ; Jialiang,Qin ^[1] ; Yu-Fei,Chen ^[1] ; Dan-Hua,He ^[1] ; Pei-En,Wu ^[1] ; Huicai,Huang ^[1] ; Ruoting,Zhan ^[1] ; Hui,Xu ^[1] ; Yong-Qiang,Liu ^[3]

作者单位： Research Center of Chinese Herbal Resources Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan, Ministry of Education, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. ^[1] Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. ^[2] Research Center of Chinese Herbal Resources Science and Engineering, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Key Laboratory of Chinese Medicinal Resource from Lingnan, Ministry of Education, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. Electronic address: liuyq@gzucm.edu.cn. ^[3]

关键词 Brusatol Metastasis NSCLC SCF complex Skp1 Skp2

主题词动物(Animals);抗肿瘤药(Antineoplastic Agents);生物素(Biotin);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);细胞系(Cell Line);人类(Humans);肺肿瘤(Lung Neoplasms);男(雄)性(Male);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);苦木素类(Quassins);S期激酶相关蛋白质类(S-Phase Kinase-Associated Proteins);小鼠(Mice)

DOI 10.1016/j.phrs.2022.106059

PMID 34998973

发布时间 2024-02-26

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Pharmacological research

2022年176卷

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Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis.

Pharmacological research

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Pharmacological research

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Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis.

Pharmacological research

相似文献

Pharmacological research

相关期刊

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