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Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries.

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作者单位: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.;Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [1] Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.;Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. [2] Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.;Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. [3] Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. [4] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Karolinska Univ Hospital, Stockholm, Sweden. [5] Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA. [6] Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. [7] Division of Evolution and Genomic Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.;Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester NIHR Biomedical Research Centre, Manchester University Hospitals NHS, Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. [8] Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.;Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.;Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia. [9] Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA. [10] Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA. [11] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.;Harvard Medical School, Boston, MA, USA. [12] Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.;Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [13] Division of Molecular Pathology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.;Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek hospital, Amsterdam, The Netherlands. [14] Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. [15] Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.;Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. [16]
DOI 10.1093/ije/dyab036
PMID 34999890
发布时间 2025-01-04
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International journal of epidemiology

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