Characteristics of sensory innervation in synovium of rats within different knee osteoarthritis models and the correlation between synovial fibrosis and hyperalgesia.
作者:
关键词
ACLT, anterior cruciate ligament transectionAnimal modelsCGRP, calcitonin gene-related peptideCWT, cold withdrawal thresholdDMM, destabilization of the medial meniscusECM, extracellular matrixKOA, knee osteoarthritisKnee osteoarthritisMIA, monoiodoacetateMWT, mechanical withdrawal thresholdNGF, nerve growth factorPainSensory innervationSynovial fibrosisTGF-β, transforming growth factor-βTRPV1, transient receptor potential vanilloid type 1TWT, thermal withdrawal thresholdVEGF, vascular endothelial growth factor
主题词
动物(Animals);疾病模型, 动物(Disease Models, Animal);纤维化(Fibrosis);痛觉过敏(Hyperalgesia);骨关节炎, 膝(Osteoarthritis, Knee);大鼠(Rats);滑膜(Synovial Membrane)
DOI
10.1016/j.jare.2021.06.007
PMID
35003798
发布时间
2022-01-26
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Journal of advanced research
2022年35卷
141-151页
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