Multi-Omics Profiling in Marfan Syndrome: Further Insights into the Molecular Mechanisms Involved in Aortic Disease.

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作者： Judith M A,Verhagen ^[1] ; Joyce,Burger ^[1] ; Jos A,Bekkers ^[2] ; Alexander T,den Dekker ^[3] ; Jan H,von der Thüsen ^[4] ; Marina,Zajec ^[5] ; Hennie T,Brüggenwirth ^[6] ; Marianne L T,van der Sterre ^[7] ; Myrthe,van den Born ^[1] ; Theo M,Luider ^[1] ; Wilfred F J,van IJcken ^[1] ; Marja W,Wessels ^[7] ; Jeroen,Essers ^[4] ; Jolien W,Roos-Hesselink ^[1] ; Ingrid,van der Pluijm ^[2] ; Ingrid M B H,van de Laar ^[8] ; Erwin,Brosens ^[9]

作者单位： Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[1] Department of Molecular Genetics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[2] Department of Cardiothoracic Surgery, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[3] Center for Biomics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[4] Department of Pathology and Clinical Bioinformatics, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[5] Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[6] Department of Neurology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[7] Department of Vascular Surgery, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[8] Department of Radiation Oncology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[9] Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands. ^[10]

关键词 Marfan syndrome RNA-seq mitochondria proteomics thoracic aortic aneurysms