A Small Peptide Targeting the Ligand-Induced Androgen Receptor/Filamin a Interaction Inhibits the Invasive Phenotype of Prostate Cancer Cells.

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作者： Marzia,Di Donato ^[1] ; Pia,Giovannelli ^[1] ; Maria Vittoria,Barone ^[2] ; Ferdinando,Auricchio ^[1] ; Gabriella,Castoria ^[1] ; Antimo,Migliaccio ^[1]

作者单位： Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy. ^[1] Department of Translational Medical Science, University of Naples "Federico II", Via S. Pansini 5, 80131 Naples, Italy. ^[2]

关键词 androgen receptor androgens cell migration prostate cancer spheroids

主题词雄激素类(Androgens);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);黏着斑蛋白酪氨酸激酶类(Focal Adhesion Protein-Tyrosine Kinases);人类(Humans);配体(Ligands);男(雄)性(Male);模型, 生物学(Models, Biological);肿瘤侵润(Neoplasm Invasiveness);肽类(Peptides);表型(Phenotype);磷酰化(Phosphorylation);前列腺肿瘤(Prostatic Neoplasms);蛋白质结合(Protein Binding);受体, 雄激素(Receptors, Androgen);球形体, 细胞(Spheroids, Cellular);转录, 遗传(Transcription, Genetic);rac1 GTP结合蛋白质(rac1 GTP-Binding Protein)

DOI 10.3390/cells11010014

PMID 35011576

发布时间 2022-03-03

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A Small Peptide Targeting the Ligand-Induced Androgen Receptor/Filamin a Interaction Inhibits the Invasive Phenotype of Prostate Cancer Cells.

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A Small Peptide Targeting the Ligand-Induced Androgen Receptor/Filamin a Interaction Inhibits the Invasive Phenotype of Prostate Cancer Cells.

Cells

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