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Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis.

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第一作者: Emmanouil,Bouras
第一单位: Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.
作者单位: Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece. [1] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, W2 1PG, UK.;Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.;Research Unit of Mathematical Sciences, University of Oulu, Oulu, Finland. [2] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, W2 1PG, UK.;Novo Nordisk Research Centre Oxford, Old Road Campus, Oxford, UK.;Clinical Pharmacology Group, Pharmacy and Medicines Directorate, St George's University Hospitals NHS Foundation Trust, London, UK.;Clinical Pharmacology and Therapeutics Section, Institute for Infection and Immunity, St George's, University of London, London, UK. [3] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, W2 1PG, UK.;Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. [4] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.;Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. [5] Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France. [6] Genomics Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France. [7] Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. [8] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.;Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. [9] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.;Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.;National Institute for Health Research (NIHR) Bristol Biomedical Research Centre, University Hospitals Bristol NHS Foundation Trust and the University of Bristol, Bristol, UK. [10] Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. [11] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. [12] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, W2 1PG, UK. [13] School of Biochemistry, University of Bristol, Bristol, UK. [14] Institute of Health Informatics, University College London, London, UK.;Health Data Research UK, London, UK. [15] Department of Community Medicine, Faculty of Health Sciences, Arctic University of Norway, Tromsø, Norway.;K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway. [16] Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nutehtal, Germany.;Institute of Nutritional Science, University of Potsdam, Potsdam, Germany. [17] Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute of Sinai Health System, Toronto, Canada.;Dalla Lana School of Public Health, University of Toronto, Toronto, Canada. [18] Baylor College of Medicine, Texas, USA. [19] The Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.;Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.;Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland. [20] Northern Finland Birth Cohorts, Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland. [21] Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland. [22] Research Unit of Biomedicine, Medical Research Center, Faculty of Medicine, University of Oulu, and Oulu University Hospital, Oulu, Finland. [23] Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. [24] Finnish Institute for Health and Welfare, Helsinki, Finland. [25] Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.;Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland. [26] MediCity Research Laboratory, University of Turku, Turku, Finland.;Institute of Biomedicine, University of Turku, Turku, Finland. [27] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, W2 1PG, UK.;Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.;Unit of Primary Care, Oulu University Hospital, Oulu, Finland. [28] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, W2 1PG, UK.;Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.;UK Dementia Research Institute at Imperial College London, London, UK. [29] Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece. k.tsilidis@imperial.ac.uk.;Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus, London, W2 1PG, UK. k.tsilidis@imperial.ac.uk. [30]
DOI 10.1186/s12916-021-02193-0
PMID 35012533
发布时间 2025-05-30
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