换一批
换一批Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques.
作者：
Takahiro,Nagatake [1]
;
Shigenobu,Kishino [2]
;
Emiko,Urano [3]
;
Haruka,Murakami [4]
;
Nahoko,Kitamura [2]
;
Kana,Konishi [4]
;
Harumi,Ohno [4]
;
Prabha,Tiwari [1]
;
Sakiko,Morimoto [1]
;
Eri,Node [1]
;
Jun,Adachi [5]
;
Yuichi,Abe [5]
;
Junko,Isoyama [6]
;
Kento,Sawane [5]
;
Tetsuya,Honda [1]
;
Asuka,Inoue [7]
;
Akiharu,Uwamizu [8]
;
Takashi,Matsuzaka [9]
;
Yoichi,Miyamoto [10]
;
So-Ichiro,Hirata [10]
;
Azusa,Saika [11]
;
Yuki,Shibata [12]
;
Koji,Hosomi [13]
;
Ayu,Matsunaga [14]
;
Hitoshi,Shimano [1]
;
Makoto,Arita [15]
;
Junken,Aoki [1]
;
Masahiro,Oka [7]
;
Akira,Matsutani [1]
;
Takeshi,Tomonaga [7]
;
Kenji,Kabashima [1]
;
Motohiko,Miyachi [1]
;
Yasuhiro,Yasutomi [16]
;
Jun,Ogawa [12]
;
Jun,Kunisawa [17]
作者单位：
Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Asagi Saito, Ibaraki, Osaka, 567-0085, Japan.
[1]
Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, 606-8502, Japan.
[2]
Laboratory of Immunoregulation and Vaccine Research, Tsukuba Primate Research Center, NIBIOHN, 1-1 Hachimandai, Tsukuba, Ibaraki, 305-0843, Japan.
[3]
Department of Physical Activity Research, NIBIOHN, 1-23-1 Toyama, Shinjuku-ku, Tokyo, 162-8636, Japan.
[4]
Laboratory of Proteome Research and Laboratory of Proteomics for Drug Discovery, NIBIOHN, 7-6-8 Asagi Saito, Ibaraki, Osaka, 567-0085, Japan.
[5]
Division of Molecular Diagnostics, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Chikusa-ku, Nagoya, 464-8681, Japan.
[6]
Graduate School of Pharmaceutical Sciences, Osaka University, 1-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
[7]
Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawara-cho, Kyoto, 606-8507, Japan.
[8]
Department of Dermatology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka, 431-3192, Japan.
[9]
Department of Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
[10]
Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
[11]
Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
[12]
Transborder Medical Research Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
[13]
Laboratory of Nuclear Transport Dynamics, NIBIOHN, 7-6-8 Asagi Saito, Ibaraki, Osaka, 567-0085, Japan.
[14]
Department of Microbiology and Immunology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan.
[15]
Faculty of Agriculture, Takasaki University of Health and Welfare, 54 Nakaoruimachi, Takasaki, Gumma, 370-0033, Japan.
[16]
Division of Physiological Chemistry and Metabolism, Keio University Faculty of Pharmacy, 1-5-30 Shibakouen, Minato-ku, Tokyo, 105-8512, Japan.
[17]
Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
[18]
Cellular and Molecular Epigenetics Laboratory, Graduate School of Medical Life Science, Yokohama City University, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan.
[19]
Department of Internal Medicine, Shunan City Shin-nanyo Hospital, 2-3-15 Miyanomae, Shunan, Yamaguchi, 746-0017, Japan.
[20]
Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Asagi Saito, Ibaraki, Osaka, 567-0085, Japan. kunisawa@nibiohn.go.jp.
[21]
Graduate School of Pharmaceutical Sciences, Osaka University, 1-1 Yamadaoka, Suita, Osaka, 565-0871, Japan. kunisawa@nibiohn.go.jp.
[22]
Department of Microbiology and Immunology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan. kunisawa@nibiohn.go.jp.
[23]
International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. kunisawa@nibiohn.go.jp.
[24]
Graduate School of Medicine, Graduate School of Dentistry, Osaka University, 1-1 Yamadaoka, Suita, Osaka, 565-0871, Japan. kunisawa@nibiohn.go.jp.
[25]
Research Organization for Nano and Life Innovation, Waseda University, Tokyo, 162-0041, Japan. kunisawa@nibiohn.go.jp.
[26]
主题词
脂肪组织(Adipose Tissue);动物(Animals);脂类(Lipids);成束猴(Macaca fascicularis);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);PPARγ(PPAR gamma)
DOI
10.1038/s41385-021-00477-5
PMID
35013573
发布时间
2023-02-03
- 浏览0
Mucosal immunology
Mucosal immunology
289-300页
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