Plasma ratio of angiopoietin-2 to angiopoietin-1 is a biomarker of vascular impairment in chronic obstructive pulmonary disease patients.

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作者： Fares,Gouzi ^[1] ; Aurélien,Philippe ^[2] ; Léo,Blervaque ^[2] ; Sven,Günther ^[3] ; Anne,Virsolvy ^[4] ; Maxime,Gruest ^[2] ; Olivier,Cazorla ^[5] ; Elisa,Rossi ^[1] ; David M,Smadja ^[2]

作者单位： INSERM - CNRS - Montpellier University, CHRU Montpellier, Montpellier, France. ^[1] Université de Paris, Innovative Therapies in Haemostasis, INSERM, F-75006, Paris, France. ^[2] Department of Hematology and Biosurgical Research Lab (Fondation Carpentier), AP-HP, Georges Pompidou European Hospital, 20 rue Leblanc, F-75015, Paris, France. ^[3] Laboratoire Interuniversitaire de Biologie de la Motricité, Université Savoie Mont Blanc, 7424, Chambéry, EA, France. ^[4] Department of Physiology AH-HP, Georges Pompidou European Hospital, F-75015, Paris, France. ^[5] Université de Paris, Innovative Therapies in Haemostasis, INSERM, F-75006, Paris, France. david.Smadja@aphp.fr. ^[6] Department of Hematology and Biosurgical Research Lab (Fondation Carpentier), AP-HP, Georges Pompidou European Hospital, 20 rue Leblanc, F-75015, Paris, France. david.Smadja@aphp.fr. ^[7]

关键词 Angiopoietins COPD Cardiopulmonary exercise test Pericyte Vessels V’O2max

主题词老年人(Aged);血管生成素1(Angiopoietin-1);血管生成素2(Angiopoietin-2);人类(Humans);中年人(Middle Aged);肺疾病, 慢性阻塞性(Pulmonary Disease, Chronic Obstructive)

DOI 10.1007/s10456-021-09826-1

PMID 35013842

发布时间 2022-07-19

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