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首页> PloS one> The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model.

The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model.

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作者： Kirsten K,Ahring ^[1] ; Frederik,Dagnæs-Hansen ^[2] ; Annemarie,Brüel ^[2] ; Mette,Christensen ^[3] ; Erik,Jensen ^[4] ; Thomas G,Jensen ^[2] ; Mogens,Johannsen ^[5] ; Karen S,Johansen ^[2] ; Allan M,Lund ^[3] ; Jesper G,Madsen ^[2] ; Karen,Brøndum-Nielsen ^[1] ; Michael,Pedersen ^[6] ; Lambert K,Sørensen ^[5] ; Mads,Kjolby ^[2] ; Lisbeth B,Møller ^[7]

作者单位： Departments of Paediatrics and Clinical Genetics, PKU Clinic, Kennedy Center, Copenhagen University Hospital, Rigshospitalet, Denmark. ^[1] Department of Biomedicine, Health, Aarhus University, Aarhus, Denmark. ^[2] Departments of Paediatrics and Clinical Genetics, Centre for Inherited Metabolic Diseases, Copenhagen University Hospital, Rigshospitalet, Denmark. ^[3] Arla Foods Ingredients Group P/S, Viby J, Denmark. ^[4] Department of Forensic Medicine, Aarhus University, Skejby, Aarhus, Denmark. ^[5] Comparative Medicine Lab, Aarhus University Hospital, Aarhus, Denmark. ^[6] Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark. ^[7] Department of Clinical Pharmacology, Aarhus University Hospital, Aarhus, Denmark. ^[8] Department of Clinical Genetics, Kennedy Center, Copenhagen University Hospital, Rigshospitalet, Denmark. ^[9]

主题词氨基酸类(Amino Acids);动物(Animals);骨密度(Bone Density);骨和骨组织(Bone and Bones);脑(Brain);酪蛋白类(Caseins);营养保健品(Dietary Supplements);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);迷宫学习(Maze Learning);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);肽碎片(Peptide Fragments);苯丙氨酸(Phenylalanine);苯丙氨酸羟化酶(Phenylalanine Hydroxylase);苯丙酮尿症(Phenylketonurias);血清素(Serotonin);酪氨酸(Tyrosine)

DOI 10.1371/journal.pone.0261150

PMID 35015767

发布时间 2022-02-15

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PloS one

PloS one

2022年17卷1期

e0261150页

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