Going green: Development of a sustainable lipid-based enteric coating formulation for low-dose aspirin multiparticulate systems.

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作者： Sonja,Schertel ^[1] ; Carolina,Corzo ^[2] ; Lukas,Leitner ^[2] ; Julia,Karrer ^[3] ; Daniel,Engel ^[2] ; Yannik,Teichmann ^[2] ; Andreas,Zimmer ^[4] ; Sharareh,Salar-Behzadi ^[5]

作者单位： University of Graz, Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology and Biopharmacy, 8010 Graz, Austria; Hermes Arzneimittel GmbH, Division Hermes Pharma, 82049 Pullach, Germany. ^[1] University of Graz, Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology and Biopharmacy, 8010 Graz, Austria; Research Center Pharmaceutical Engineering GmbH, 8010 Graz, Austria. ^[2] Research Center Pharmaceutical Engineering GmbH, 8010 Graz, Austria. ^[3] University of Graz, Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology and Biopharmacy, 8010 Graz, Austria. ^[4] University of Graz, Institute of Pharmaceutical Sciences, Department of Pharmaceutical Technology and Biopharmacy, 8010 Graz, Austria; Research Center Pharmaceutical Engineering GmbH, 8010 Graz, Austria. Electronic address: Sharareh.salar@rcpe.at. ^[5]

关键词 Acetylsalicylic acid Enteric-coated Gastric-resistance Lipid-based Solid-state stability Solvent-free hot melt coating