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Neomenthol prevents the proliferation of skin cancer cells by restraining tubulin polymerization and hyaluronidase activity.

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第一作者: Kaneez,Fatima
第一单位: Bioprospection and Product Development Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, Uttar Pradesh, India.;Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, Uttar Pradesh, India.
作者: Kaneez,Fatima [1] ; Nusrat,Masood [2] ; Zahoor,Ahmad Wani [2] ; Abha,Meena [1] ; Suaib,Luqman [1]
作者单位: Bioprospection and Product Development Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, Uttar Pradesh, India.;Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, Uttar Pradesh, India. [1] Bioprospection and Product Development Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow 226015, Uttar Pradesh, India. [2]
关键词 AA, Arachidonic acidAKLP, Alkaline phosphataseAb/Am, Antibiotic/antimycoticBE, Binding energyBIL, Bilirubin total & directBSA, Bovine serum albuminBUN, Blood urea nitrogenCATD, Cathepsin DCHOL, CholesterolCM-H2DCFDA, Chloromethyl derivative of dichloro fluorescin diacetateCOX-2, Cyclooxygenase 2CRTN, CreatinineCancer biomarkerDCFDA, 2′,7′ dichloro fluorescin diacetateDFMO, α-difluoro methyl ornithineDHFR, DihydrofolatereductaseDMEM, Dulbecco’s minimal essential mediaDMSO, Dimethyl sulfoxideDNA, Deoxyribonucleic acidDOXO, DoxorubicinEAC, Ehlrich Ascites CarcinomaEC50, Half maximal effective concentrationEDTA, Ethylene diamine tetra acetic acidELISA, enzyme-linked immunosorbent assayEhrlich Ascites CarcinomaFACS, Fluorescence-Activated Cell SortingFBS, Fetal bovine serumFDA, Food and Drug AdministrationFOX, Ferrous oxidation-xylenol orangeGAPDH, Glyceraldehyde 3-phosphate dehydrogenase, HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acidHA, Hyaluronic acidHDAC, Histone deacetylaseHDL, High density lipoproteinHYAL, HyaluronidaseHuman epidermoid carcinomaHyaluronidaseIC50, Half maximal inhibitory concentrationIDT, Integrated DNA TechnologiesKi, Inhibitory constantLDH, Lactate dehydrogenaseLOX-5, Lipoxygenase-5MEF, Mean erythrocyte fragilityMMP, Mitochondrial membrane potentialMTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideMTX, MethotrexateNAC, N-acetyl cysteineNADPH, Nicotinamide adenine dinucleotide phosphate hydrogenNRU, Neutral red uptakeNaOH, Sodium hydroxideNeomentholODC, Ornithine decarboxylaseOECD, Organization for Economic Co-operation and DevelopmentOF, Osmotic fragilityPBS, Phosphate buffer salinePCR, Polymerase chain reactionPDB, Protein Data BankPDT, PodophyllotoxinPEP A, pepstatin API, Propidium iodidePI3K, Phosphotidyl inositol-3 kinasePKB/Akt, Protein kinase BRBC, Red blood cellRIPA, Radio immune precipitation assay bufferRNA, Ribonucleic acidRNase A, Ribonuclease AROS, Reactive oxygen speciesRPMI, Roswell park memorial instituteRh123, Rhodamine 123SGOT, Aspartate aminotransferaseSGPT, Alanine aminotransferaseSRB, Sulphorhodamine BTCA, Tricarboxylic acidTMPD, N,N,N′,N′-tetramethyl-p-phenylenediamineTNBS, Trinitrobenzenesulphonic acidTPA, 12-O-Tetradecanoylphorbol-13-acetateTPR, Total proteinTRIG, TriglyceraldehydeTRPM8, Transient receptor potential member 8TubulinURIC, Uric acidWBC, White blood cellmTOR, Mammalian target of rapamycin
DOI 10.1016/j.jare.2021.06.003
PMID 35024183
发布时间 2022-01-26
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Journal of advanced research

Journal of advanced research

2021年34卷

93-107页

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