Pre-administration of a carboxypeptidase inhibitor enhances tPA-induced thrombolysis in mouse microthrombi: Evidence from intravital imaging analysis.

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第一作者： Nitty Skariah,Mathews

第一单位： Department of Medical Physiology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka 431-3192, Japan. Electronic address: nsmathews@cmcvellore.ac.in.

作者： Nitty Skariah,Mathews ^[1] ; Yuko,Suzuki ^[2] ; Naoki,Honkura ^[3] ; Hideto,Sano ^[4] ; Toshihide,Iwashita ^[5] ; Tetsumei,Urano ^[6]

作者单位： Department of Medical Physiology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka 431-3192, Japan. Electronic address: nsmathews@cmcvellore.ac.in. ^[1] Department of Medical Physiology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka 431-3192, Japan. Electronic address: seigan@hama-med.ac.jp. ^[2] Department of Medical Physiology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka 431-3192, Japan. Electronic address: pon@hama-med.ac.jp. ^[3] Department of Medical Physiology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka 431-3192, Japan. Electronic address: sano@hama-med.ac.jp. ^[4] Department of Regenerative & Infectious Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka 431-3192, Japan. Electronic address: toshiiwa@hama-med.ac.jp. ^[5] Department of Medical Physiology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu city, Shizuoka 431-3192, Japan; Shizuoka Graduate University of Public Health, 4-17-2, Kita-Ando, Aoi-ku Shizuoka 420-0882, Japan. Electronic address: uranot@hama-med.ac.jp. ^[6]

关键词 Carboxypeptidase inhibitor Glu-plasminogen TAFI Thrombolysis Two-photon microscopy rt-PA