ZC3H13-mediated N6-methyladenosine modification of PHF10 is impaired by fisetin which inhibits the DNA damage response in pancreatic cancer.

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第一作者： Chaojie,Huang

第一单位： Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: huang123hcj@163.com.

作者： Chaojie,Huang ^[1] ; Senhao,Zhou ^[2] ; Chaolei,Zhang ^[3] ; Yifeng,Jin ^[4] ; Gao,Xu ^[5] ; Liangjing,Zhou ^[6] ; Guoping,Ding ^[7] ; Tianshu,Pang ^[8] ; Shengnan,Jia ^[9] ; Liping,Cao ^[10]

作者单位： Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: huang123hcj@163.com. ^[1] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: 11918317@zju.edu.cn. ^[2] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: 22018136@zju.edu.cn. ^[3] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: 21918350@zju.edu.cn. ^[4] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: 519016054@qq.com. ^[5] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: 21318087@zju.edu.cn. ^[6] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: dinguop@zju.edu.cn. ^[7] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: ptslhc@126.com. ^[8] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: jiashengnan8180@zju.edu.cn. ^[9] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China; Zhejiang Engineering Research Center of Cognitive Healthcare, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, 310000, China. Electronic address: caolipingzju@zju.edu.cn. ^[10]

关键词 DNA damage response Fisetin N6-methyladenosine modification PHF10 ZC3H13