Shallow whole-genome sequencing: a useful, easy to apply molecular technique for CNA detection on FFPE tumor tissue-a glioma-driven study.

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作者： Kim,Van der Eecken ^[1] ; Malaïka,Van der Linden ^[2] ; Lennart,Raman ^[1] ; David,Creytens ^[2] ; Franceska,Dedeurwaerdere ^[3] ; Koen,De Winne ^[1] ; Liesbeth,Ferdinande ^[3] ; Martin,Lammens ^[1] ; Björn,Menten ^[2] ; Isabelle,Rottiers ^[4] ; Bram,Van Gaever ^[5] ; Caroline,Van den Broecke ^[1] ; Koen,Van de Vijver ^[2] ; Nadine,Van Roy ^[5] ; Sofie,Verbeke ^[2] ; Jo,Van Dorpe ^[3]

作者单位： Department of Pathology, Ghent University, Ghent University Hospital, Ghent, Belgium. ^[1] Cancer Research Institute (CRIG), Ghent, Belgium. ^[2] Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Ghent University Hospital, Ghent, Belgium. ^[3] Department of Pathology, AZ Delta, Roeselare, Belgium. ^[4] Department of Pathology, Antwerp University Hospital, Antwerp, Belgium. ^[5] Department of Pathology, AZ Sint-Lucas, Ghent, Belgium. ^[6] Department of Pathology, Ghent University, Ghent University Hospital, Ghent, Belgium. jo.vandorpe@uzgent.be. ^[7] Cancer Research Institute (CRIG), Ghent, Belgium. jo.vandorpe@uzgent.be. ^[8]

关键词 1p/19q codeletion Copy number aberration detection Fluorescence in situ hybridization Glial tumors Shallow whole-genome sequencing