首页> Frontiers in medicine> Hydroxylation of N-acetylneuraminic Acid Influences the in vivo Tropism of N-linked Sialic Acid-Binding Adeno-Associated Viruses AAV1, AAV5, and AAV6.

Hydroxylation of N-acetylneuraminic Acid Influences the in vivo Tropism of N-linked Sialic Acid-Binding Adeno-Associated Viruses AAV1, AAV5, and AAV6.

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第一作者： Estrella,Lopez-Gordo

第一单位： Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, United States.

作者： Estrella,Lopez-Gordo ^[1] ; Alejandro,Orlowski ^[1] ; Arthur,Wang ^[1] ; Alan,Weinberg ^[2] ; Susmita,Sahoo ^[1] ; Thomas,Weber ^[3]

作者单位： Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, United States. ^[1] Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York City, NY, United States. ^[2] Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, United States.;Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York City, NY, United States. ^[3]

关键词 N-acetylneuraminic acid N-glycolylneuraminic acid adeno-associated virus animal model sialic acid tropism

DOI 10.3389/fmed.2021.732095

PMID 35036407

发布时间 2022-01-20

基金项目

R01 HL131404/HL/NHLBI NIH HHS/United States R01 HL140469/HL/NHLBI NIH HHS/United States R01 HL148786/HL/NHLBI NIH HHS/United States

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Hydroxylation of <i>N</i>-acetylneuraminic Acid Influences the <i>in vivo</i> Tropism of <i>N</i>-linked Sialic Acid-Binding Adeno-Associated Viruses AAV1, AAV5, and AAV6.

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Hydroxylation of <i>N</i>-acetylneuraminic Acid Influences the <i>in vivo</i> Tropism of <i>N</i>-linked Sialic Acid-Binding Adeno-Associated Viruses AAV1, AAV5, and AAV6.

Frontiers in medicine

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