Effect of P2Y12 Inhibitors on Survival Free of Organ Support Among Non-Critically Ill Hospitalized Patients With COVID-19: A Randomized Clinical Trial.-论文-万方医学网

第一作者： Jeffrey S,Berger

第一单位： NYU Grossman School of Medicine, New York, New York.

作者： Jeffrey S,Berger ^[1] ; Lucy Z,Kornblith ^[2] ; Michelle N,Gong ^[3] ; Harmony R,Reynolds ^[1] ; Mary,Cushman ^[4] ; Yu,Cheng ^[5] ; Bryan J,McVerry ^[5] ; Keri S,Kim ^[6] ; Renato D,Lopes ^[7] ; Bassel,Atassi ^[8] ; Scott,Berry ^[9] ; Grant,Bochicchio ^[10] ; Murillo,de Oliveira Antunes ^[11] ; Michael E,Farkouh ^[12] ; Yonatan,Greenstein ^[13] ; Erinn M,Hade ^[1] ; Kristin,Hudock ^[14] ; Robert,Hyzy ^[15] ; Pooja,Khatri ^[14] ; Andrei,Kindzelski ^[16] ; Bridget-Anne,Kirwan ^[17] ; Lisa,Baumann Kreuziger ^[18] ; Patrick R,Lawler ^[12] ; Eric,Leifer ^[16] ; Jose,Lopez-Sendon Moreno ^[19] ; Jose,Lopez-Sendon ^[20] ; James F,Luther ^[5] ; Lilia,Nigro Maia ^[21] ; John,Quigley ^[6] ; Robert,Sherwin ^[22] ; Lana,Wahid ^[23] ; Jennifer,Wilson ^[24] ; Judith S,Hochman ^[1] ; Matthew D,Neal ^[5] ; ACTIV-4a Investigators

作者单位： NYU Grossman School of Medicine, New York, New York. ^[1] University of California, San Francisco. ^[2] Albert Einstein College of Medicine, Bronx, New York. ^[3] College of Medicine, University of Vermont, Burlington. ^[4] University of Pittsburgh, Pittsburgh, Pennsylvania. ^[5] University of Illinois, Chicago. ^[6] Duke University Medical Center, Durham, North Carolina. ^[7] OSF Little Company of Mary Medical Center, Evergreen Park, Illinois. ^[8] Berry Consultants LLC, Austin, Texas. ^[9] School of Medicine, Washington University, St Louis, Missouri. ^[10] Hospital Universitario São Francisco de Assis, São Paulo, Brazil. ^[11] Peter Munk Cardiac Centre, Toronto, Ontario, Canada. ^[12] New Jersey Medical School, Rutgers University, Newark. ^[13] University of Cincinnati Medical Center, Cincinnati, Ohio. ^[14] University of Michigan, Ann Arbor. ^[15] National Heart, Lung, and Blood Institute, Bethesda, Maryland. ^[16] Socar Research SA, Nyon, Switzerland. ^[17] Versity Blood Research Institute, Milwaukee, Wisconsin. ^[18] Hospital Universitario Ramon Y Cajal, Madrid, Spain. ^[19] Hospital Universitario La Paz, Madrid, Spain. ^[20] Fundação Faculdade Regional De Medicina De São José Do Rio Preto, São José do Rio Preto, Brazil. ^[21] Wayne State University, Detroit, Michigan. ^[22] Duke University Hospital, Durham, North Carolina. ^[23] Stanford University Medical Center, Stanford, California. ^[24]

医学主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);抗凝药(Anticoagulants);共病现象(Comorbidity);体外膜氧合作用(Extracorporeal Membrane Oxygenation);女(雌)性(Female);出血(Hemorrhage);肝素(Heparin);医院死亡率(Hospital Mortality);人类(Humans);住院病人(Inpatients);男(雄)性(Male);医疗无效(Medical Futility);中年人(Middle Aged);氧吸入疗法(Oxygen Inhalation Therapy);血小板活化(Platelet Activation);血小板聚集抑制剂(Platelet Aggregation Inhibitors);嘌呤能P2Y受体拮抗剂(Purinergic P2Y Receptor Antagonists);受体, 嘌呤能P2Y12(Receptors, Purinergic P2Y12);呼吸, 人工(Respiration, Artificial);血栓形成(Thrombosis);时间因素(Time Factors);治疗结果(Treatment Outcome)

DOI 10.1001/jama.2021.23605

PMID 35040887

发布时间 2025-07-21

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Effect of P2Y12 Inhibitors on Survival Free of Organ Support Among Non-Critically Ill Hospitalized Patients With COVID-19: A Randomized Clinical Trial.

JAMA

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Effect of P2Y12 Inhibitors on Survival Free of Organ Support Among Non-Critically Ill Hospitalized Patients With COVID-19: A Randomized Clinical Trial.

JAMA

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JAMA

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