CRISPR/CasRx Proof-of-Concept for RNA Degradation: A Future Tool against RNA Viruses?

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作者： Diana,Perez-SanJose ^[1] ; Miguel Angel,de la Fuente ^[2] ; Julia,Serna Pérez ^[2] ; Maria,Simarro ^[3] ; José María,Eiros Bouza ^[2] ; Ivan,Sanz-Muñoz ^[4]

作者单位： National Influenza Center of Valladolid, Hospital Clínico Universitario de Valladolid, University of Valladolid, 47010 Valladolid, Spain. ^[1] Targeted Gene Modification Laboratory, Unidad de Excelencia Instituto de Biología y Genética Molecular (IBGM), 47003 Valladolid, Spain. ^[2] Department of Cell Biology, Histology and Pharmacology, University of Valladolid, 47005 Valladolid, Spain. ^[3] Department of Biochemistry and Molecular Biology and Physiology, University of Valladolid, 47005 Valladolid, Spain. ^[4] Nursing Unit, Nursing Faculty, University of Valladolid, 47005 Valladolid, Spain. ^[5] Microbiology Service, Hospital Universitario Río Hortega, 47012 Valladolid, Spain. ^[6]

关键词 CRISPR/Cas system CRISPR/Cas13d CRISPR/CasRx antiviral influenza virus

DOI 10.3390/ph15010032

PMID 35056089

发布时间 2022-01-28

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