Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle cerebral artery occlusion.

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作者： Xiaowen,Hu ^[1] ; Jiaji,Pan ^[1] ; Yongfang,Li ^[2] ; Yixu,Jiang ^[1] ; Haoran,Zheng ^[1] ; Rubing,Shi ^[1] ; Qi,Zhang ^[1] ; Chang,Liu ^[1] ; Hengli,Tian ^[1] ; Zhijun,Zhang ^[1] ; Yaohui,Tang ^[1] ; Guo-Yuan,Yang ^[3] ; Yongting,Wang ^[4]

作者单位： Shanghai Sixth People's Hospital and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China. ^[1] Department of Rehabilitation and Institute of Neurology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China. ^[2] Shanghai Sixth People's Hospital and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China. gyyang@sjtu.edu.cn. ^[3] Department of Rehabilitation and Institute of Neurology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200025, China. gyyang@sjtu.edu.cn. ^[4] Shanghai Sixth People's Hospital and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China. ytwang@sjtu.edu.cn. ^[5]

关键词 Adipose-derived stem cell Cerebral ischemia Extracellular vesicles Microglial polarization miRNAs