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An overlooked subset of Cx3cr1<sup>wt/wt</sup> microglia in the Cx3cr1<sup>CreER-Eyfp/wt</sup> mouse has a repopulation advantage over Cx3cr1<sup>CreER-Eyfp/wt</sup> microglia following microglial depletion.

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作者单位: Henan Neurodevelopment Engineering Research Center for Children, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, China. kai.zhou@ki.se. [1] Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden. kai.zhou@ki.se. [2] Applied Immunology and Immunotherapy, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden. [3] Neuroimmunology Center, Department of Neurology, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, China. [4] Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden. [5] Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden. [6] Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany. [7] University of Tuebingen, Tuebingen, Germany. [8] Department of Obstetrics and Gynecology, Nagoya City University Hospital, Nagoya, Japan. [9] Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden. [10] Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan. [11] Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden. [12] WHO-Centre, Karolinska University Hospital, Stockholm, Sweden. [13] Department of Medicine Huddinge, Karolinska Institutet, Campus Flemingsberg, Huddinge, Sweden. [14] Centre for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden. [15] Henan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, The Third Affiliated Hospital and Institute of Neuroscience, Zhengzhou University, Zhengzhou, China. [16] Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. [17] Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden. klas.blomgren@ki.se. [18] Henan Key Laboratory of Child Brain Injury and Henan Pediatric Clinical Research Center, The Third Affiliated Hospital and Institute of Neuroscience, Zhengzhou University, Zhengzhou, China. klas.blomgren@ki.se. [19] Pediatric Oncology, Karolinska University Hospital, Stockholm, Sweden. klas.blomgren@ki.se. [20]
DOI 10.1186/s12974-022-02381-6
PMID 35062962
发布时间 2022-04-07
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Journal of neuroinflammation

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