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CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells.

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作者单位: Research Programs Unit, Stem cells and Metabolism and Biomedicum Stem Cell Centre, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland. [1] Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm 14183, Sweden. [2] Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki 00014, Finland; Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki 00014, Finland; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki 00014, Finland; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK. [3] Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona 08003, Spain. [4] Research Programs Unit, Stem cells and Metabolism and Biomedicum Stem Cell Centre, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Stockholm 14183, Sweden; Folkhälsan Research Center, Helsinki 00290, Finland. [5] Finnish Institute for Health and Welfare (THL), THL Biobank, Helsinki 00290, Finland. [6] Research Programs Unit, Stem cells and Metabolism and Biomedicum Stem Cell Centre, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland; Children's Hospital, Helsinki University Central Hospital, University of Helsinki, Helsinki 00290, Finland. [7] Research Programs Unit, Stem cells and Metabolism and Biomedicum Stem Cell Centre, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland; Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Huddinge, Stockholm 14186, Sweden; Division of Obstetrics and Gynecology, Karolinska Universitets Sjukhuset, Huddinge, Stockholm 14186, Sweden. [8] Research Programs Unit, Stem cells and Metabolism and Biomedicum Stem Cell Centre, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland. Electronic address: ras.trokovic@helsinki.fi. [9]
DOI 10.1016/j.stemcr.2021.12.017
PMID 35063129
发布时间 2022-03-23
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Stem cell reports

Stem cell reports

2022年17卷2期

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