Translational Approaches for Brain Delivery of Biologics via Cerebrospinal Fluid.

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作者： Shraddha S,Sadekar ^[1] ; Mayumi,Bowen ^[2] ; Hao,Cai ^[1] ; Samira,Jamalian ^[1] ; Hanine,Rafidi ^[1] ; Whitney,Shatz-Binder ^[1] ; Julien,Lafrance-Vanasse ^[1] ; Pamela,Chan ^[1] ; William J,Meilandt ^[1] ; Amy,Oldendorp ^[1] ; Alavattam,Sreedhara ^[2] ; Ann,Daugherty ^[2] ; Susan,Crowell ^[1] ; Kristin R,Wildsmith ^[3] ; Jasvinder,Atwal ^[1] ; Reina N,Fuji ^[1] ; Joshua,Horvath ^[2]

作者单位： Genentech Research and Early Development, Genentech, Inc., a Member of the Roche Group, San Francisco, California, USA. ^[1] Pharma Technical Development, Genentech, Inc., a Member of the Roche Group, San Francisco, California, USA. ^[2] Clinical Pharmacology and Translational Medicine, Neurology Business, Eisai, Nutley, New Jersey, USA. ^[3]

主题词生物制品(Biological Products);生物转运(Biological Transport);血脑屏障(Blood-Brain Barrier);脑(Brain);中枢神经系统(Central Nervous System);人类(Humans)

DOI 10.1002/cpt.2531

PMID 35064573

发布时间 2022-07-27

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