Real-Life Turning Movements Capture Subtle Longitudinal and Preataxic Changes in Cerebellar Ataxia.

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第一作者： Annika,Thierfelder

第一单位： Section Computational Sensomotorics, Hertie Institute for Clinical Brain Research, Otfried-Müller-Straße 27, Tübingen, 72076, Germany.;Centre for Integrative Neuroscience (CIN), Otfried-Müller-Straße 25, Tübingen, 72076, Germany.

作者： Annika,Thierfelder ^[1] ; Jens,Seemann ^[1] ; Natalie,John ^[2] ; Florian,Harmuth ^[3] ; Martin,Giese ^[1] ; Rebecca,Schüle ^[4] ; Ludger,Schöls ^[4] ; Dagmar,Timmann ^[5] ; Matthis,Synofzik ^[4] ; Winfried,Ilg ^[1]

作者单位： Section Computational Sensomotorics, Hertie Institute for Clinical Brain Research, Otfried-Müller-Straße 27, Tübingen, 72076, Germany.;Centre for Integrative Neuroscience (CIN), Otfried-Müller-Straße 25, Tübingen, 72076, Germany. ^[1] Section Computational Sensomotorics, Hertie Institute for Clinical Brain Research, Otfried-Müller-Straße 27, Tübingen, 72076, Germany.;Department of Neurodegeneration, Hertie Institute for Clinical Brain Research and Centre of Neurology, Otfried-Müller-Straße 27, Tübingen, 72076, Germany. ^[2] Institute of Medical Genetics and Applied Genomics, University Hospital Tübingen, Calwerstr. 7, Tübingen, 72076, Germany. ^[3] Department of Neurodegeneration, Hertie Institute for Clinical Brain Research and Centre of Neurology, Otfried-Müller-Straße 27, Tübingen, 72076, Germany.;German Research Center for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 23, Tübingen, 72076, Germany. ^[4] Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), University of Duisburg-Essen, Hufelandstrasse 55, Essen, 45147, Germany. ^[5]

关键词 cerebellar ataxia motor biomarker real-life walking turning wearable sensors

主题词共济失调(Ataxia);小脑共济失调(Cerebellar Ataxia);横断面研究(Cross-Sectional Studies);人类(Humans);纵向研究(Longitudinal Studies);脊髓小脑共济失调(Spinocerebellar Ataxias)

DOI 10.1002/mds.28930

PMID 35067979

发布时间 2022-06-29

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