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首页> Drug delivery> Hybrid thermosensitive-mucoadhesive <i>in situ</i> forming gels for enhanced corneal wound healing effect of L-carnosine.

Hybrid thermosensitive-mucoadhesive <i>in situ</i> forming gels for enhanced corneal wound healing effect of L-carnosine.

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作者： Zeinab,Fathalla ^[1] ; Wesam W,Mustafa ^[2] ; Hamdy,Abdelkader ^[3] ; Hossam,Moharram ^[1] ; Ahmed Mohamed,Sabry ^[4] ; Raid G,Alany ^[5]

作者单位： Pharmaceutics Department, Faculty of Pharmacy, Minia University, Minia, Egypt. ^[1] Department of Chemical and Pharmaceutical Sciences, Kingston University London, Kingston upon Thames, UK. ^[2] Department of Pharmacy, Al-Mustafa University College, Baghdad, Iraq. ^[3] Pharmaceutics Department, Faculty of Pharmacy, Deraya University, New Minia, Egypt. ^[4] Ophthalmology Department, Faculty of Medicine, Minia University, Minia, Egypt. ^[5] Drug Discovery, Delivery and Patient Care Theme, Faculty of Science, Engineering and Computing, Kingston University, Kingston upon Thames, UK. ^[6] School of Pharmacy, The University of Auckland, Auckland, New Zealand. ^[7]

关键词 L-carnosine cornea gelation time and temperature in situ gel-forming ocular delivery texture analysis

主题词投药, 局部(Administration, Topical);动物(Animals);肌肽(Carnosine);化学, 药物(Chemistry, Pharmaceutical);壳聚糖(Chitosan);角膜(Cornea);角膜溃疡(Corneal Ulcer);迟效制剂(Delayed-Action Preparations);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物释放系统(Drug Delivery Systems);凝胶类(Gels);甲基纤维素(Methylcellulose);泊洛沙姆(Poloxamer);兔(Rabbits);流变学(Rheology);温度(Temperature);伤口愈合(Wound Healing)

DOI 10.1080/10717544.2021.2023236

PMID 35068268

发布时间 2022-04-30

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2022年29卷1期

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