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Communicating regulatory high-throughput sequencing data using BioCompute Objects.

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第一作者： Charles Hadley S,King

第一单位： The Department of Biochemistry & Molecular Medicine, The George Washington University Medical Center, Washington, DC 20037, USA; The McCormick Genomic and Proteomic Center, The George Washington University, Washington, DC 20037, USA.

作者： Charles Hadley S,King ^[1] ; Jonathon,Keeney ^[2] ; Nuria,Guimera ^[3] ; Souvik,Das ^[3] ; Michiel,Weber ^[3] ; Brian,Fochtman ^[2] ; Mark O,Walderhaug ^[4] ; Sneh,Talwar ^[2] ; Janisha A,Patel ^[2] ; Raja,Mazumder ^[1] ; Eric F,Donaldson ^[5]

作者单位： The Department of Biochemistry & Molecular Medicine, The George Washington University Medical Center, Washington, DC 20037, USA; The McCormick Genomic and Proteomic Center, The George Washington University, Washington, DC 20037, USA. ^[1] The Department of Biochemistry & Molecular Medicine, The George Washington University Medical Center, Washington, DC 20037, USA. ^[2] DDL Diagnostic Laboratory, 2288 ER Rijswijk, the Netherlands. ^[3] US Food and Drug Administration, Silver Spring, MD 20993, USA. ^[4] US Food and Drug Administration, Silver Spring, MD 20993, USA. Electronic address: Eric.Donaldson@fda.hhs.gov. ^[5]

关键词 Amino acid substitutions Antiviral resistance BioCompute Objects HCV1a Next generation sequencing (NGS)Regulatory submission Single nucleotide polymorphism (SNP)

医学主题词高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);药用制剂(Pharmaceutical Preparations);结果可重复性(Reproducibility of Results);美国(United States);美国食品和药物管理局(United States Food and Drug Administration)

DOI 10.1016/j.drudis.2022.01.007

PMID 35077912

发布时间 2022-04-20

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