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Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource.

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第一作者： Lisa,Dressler

第一单位： Cancer Systems Biology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;School of Cancer and Pharmaceutical Sciences, King's College London, London, SE11UL, UK.;Department of Medical and Molecular Genetics, King's College London, London, SE1 9RT, UK.

作者： Lisa,Dressler ^[1] ; Michele,Bortolomeazzi ^[2] ; Mohamed Reda,Keddar ^[2] ; Hrvoje,Misetic ^[2] ; Giulia,Sartini ^[2] ; Amelia,Acha-Sagredo ^[2] ; Lucia,Montorsi ^[2] ; Neshika,Wijewardhane ^[2] ; Dimitra,Repana ^[2] ; Joel,Nulsen ^[2] ; Jacki,Goldman ^[3] ; Marc,Pollitt ^[3] ; Patrick,Davis ^[3] ; Amy,Strange ^[3] ; Karen,Ambrose ^[3] ; Francesca D,Ciccarelli ^[4]

作者单位： Cancer Systems Biology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;School of Cancer and Pharmaceutical Sciences, King's College London, London, SE11UL, UK.;Department of Medical and Molecular Genetics, King's College London, London, SE1 9RT, UK. ^[1] Cancer Systems Biology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK.;School of Cancer and Pharmaceutical Sciences, King's College London, London, SE11UL, UK. ^[2] Scientific Computing, The Francis Crick Institute, London, NW1 1AT, UK. ^[3] Cancer Systems Biology Laboratory, The Francis Crick Institute, London, NW1 1AT, UK. francesca.ciccarelli@crick.ac.uk.;School of Cancer and Pharmaceutical Sciences, King's College London, London, SE11UL, UK. francesca.ciccarelli@crick.ac.uk. ^[4]

关键词 Cancer initiation Driver genes Somatic evolution Systems-level properties

医学主题词人类(Humans);突变(Mutation);肿瘤(Neoplasms);癌基因(Oncogenes)

DOI 10.1186/s13059-022-02607-z

PMID 35078504

发布时间 2022-04-05

基金项目

C43634/A25487/CRUK_/Cancer Research UK/United Kingdom C604/A25135/CRUK_/Cancer Research UK/United Kingdom C7893/A26233/CRUK_/Cancer Research UK/United Kingdom FC001002/WT_/Wellcome Trust/United Kingdom WT_/Wellcome Trust/United Kingdom

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