Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription.

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第一作者： Liping,Yang

第一单位： Department of Infectious Diseases, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China; Suzhou Institute of Systems Medicine, Suzhou 215123, China.

作者： Liping,Yang ^[1] ; Shengchuan,Chen ^[2] ; Qun,Zhao ^[3] ; Chaohu,Pan ^[4] ; Linan,Peng ^[5] ; Yu,Han ^[1] ; Lili,Li ^[4] ; Jiayin,Ruan ^[4] ; Jingyan,Xia ^[6] ; Heng,Yang ^[7] ; Feng,Xu ^[8] ; Genhong,Cheng ^[9]

作者单位： Department of Infectious Diseases, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China; Suzhou Institute of Systems Medicine, Suzhou 215123, China. ^[1] Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China; Suzhou Institute of Systems Medicine, Suzhou 215123, China; Department of Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China. ^[2] CAS Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China. ^[3] Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China; Suzhou Institute of Systems Medicine, Suzhou 215123, China. ^[4] School of Medicine, Xiamen University, Xiamen 361000, China. ^[5] Department of Radiation Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China. ^[6] Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China; Suzhou Institute of Systems Medicine, Suzhou 215123, China. Electronic address: yhmyt@hotmail.com. ^[7] Department of Infectious Diseases, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China. Electronic address: xufeng99@zju.edu.cn. ^[8] Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: gcheng@mednet.ucla.edu. ^[9]

关键词 FOXK1 HDAC3 STAT1 STAT2 transcription regulation type I interferon